Role: Sets vision and direction for company. Experience: Over 15 years working on Parkinson's disease. Founding CEO at NeuroInitiative since 2014 where she laid out a vision for applying advanced computational drug discovery methods, which led to Vincere's pipeline. Previously she worked with Matt Farrer at Mayo clinic to characterize genetic models of Parkinson's disease and was part of the team that discovered a new pathogenic mutation in VPS35. Her PhD work implemented cutting-edge laser capture, microarray, and in vivo siRNA techniques to identify protective genomic changes in Parkinson’s models. Recipient of JBJ’s 40 under 40 award, winner of One Spark’s science award, and supporter of science on the TEDx and March for Science stages. Education: PhD in Neuroscience from Michigan State University, postdoctoral work at Mayo Clinic. Favorite Quote: "The best way to predict the future is to invent it." - Alan Kay
Role: Responsible for Technology, Licensing, and Operations Experience: Over 20 years software and management experience in multiple industries. Founding CTO at NeuroInitiative where he is co-inventor on multiple granted and pending patents surrounding the SEED simulation platform. Previously VP of Engineering at Black Knight through F500 acquisition, spin-out, and IPO. He has led teams of over 100 members and continues to actively code to create new data-driven solutions. Education: B.S. Computer Science from Grand Valley State University. Postgraduate coursework at Michigan State University. Favorite Quote: "For a successful technology, reality must take precedence over public relations, for nature cannot be fooled." - Richard Feynman
Role: Advises on business strategy and fundraising.
Experience: Angel investor with 30 years of business strategy and finance experience. Former Head of the Global Technology Banking Group at Morgan and Chief Strategy Officer for IBM’s Services Division. Education: Graduated from Phillips Exeter Academy, holds a Sc.B. in Applied Mathematics/Economics from Brown University, and an MBA in Finance/Marketing from the University of Chicago Graduate School of Business. Favorite Quote: "Behold the turtle. He makes progress only when he sticks his neck out." - James Bryant Conant
Role: Leads biology and assay design Experience: Over 15 years experience building biology and drug discovery programs at big pharma (AstraZeneca) and biotech (Hydra Biosciences and Mnemosyne (now Cadent)). Chris has established assay design and built successful early discovery teams, which he will do again here at Vincere. He brings extensive expertise in ion channels and electrophysiology. Education: PhD in Immunology from Stanford and postdoctoral work at UC Irvine. Favorite Quote: “In questions of science, the authority of a thousand is not worth the humble reasoning of a single individual.” - Galileo Galilei
Role: Leads new compound design. Experience: More than 25 years of medicinal chemistry experience doing drug discovery in a variety of therapeutic areas for both large pharma (Upjohn, Pharmacia and Pfizer) and biotech. She also serves as a consultant to the NIH NINDS Blueprint program helping small biotechs and academic groups discover drugs for a variety of CNS indications. She has extensive experience in all aspects of drug discovery and design including hit identification, lead optimization, structure-based drug design, preclinical development and early API strategy. Education: Phd Organic Chemistry from University of Wisconsin-Madison Favorite Quote: "Not everything that can be counted counts. Not everything that counts can be counted." - William Bruce Cameron
Role: Aids new compound design
Experience: Over 40 years of experience in drug discovery research at major pharmaceutical companies including The Upjohn Co, Pharmacia, and Pfizer as well as small biotech companies. Expert in the areas of traditional synthetic chemistry, compound library design and high speed automated organic synthesis. Contributed to programs across many therapeutic areas including Infectious Diseases, Cancer, Atherosclerosis, Metabolic Diseases and Hypersensitivity Diseases. Skilled in all aspects of drug discovery research from hit identification, lead finding/ optimization to identification of drug candidates. Authored or co-Authored 11 publications and co-inventor of many patents. Education: BA Chemistry, The University of Notre Dame, MS Organic Chemistry, The Ohio State University. Favorite Quote: "Science can make man comfortable, but only wisdom can make man happy." – Rev. Theodore Hesburgh
Role: Provides executive and logistical support Experience: Previously founded and developed a Vietnamese online educational startup. Five years of teaching, EdTech, and startup management. Education: Harvard University Ongoing Favorite Quote: “Two things fill the mind with ever new and increasing admiration and awe, the more often and steadily we reflect upon them: the starry heavens above me and the moral law within me.” - Immanuel Kant
Interested in joining our team? Check out the careers page for current openings.
Role: Parkinson's and biochemistry expertise. Experience: Director of the Medical Research Council Protein Phosphorylation and Ubiquitylation unit at University of Dundee. Alessi has spent decades characterizing how phosphorylation and ubiquitylation cascades control biological function and disease resulting in 275 manuscripts which have been cited over 70,000 times establishing his role as a leader of the field. Education: BSc and PhD in Biochemistry from the University of Birmingham with postdoctoral research in the MRC PPU.
Role: Structural Biology expertise. Experience: Currently professor and Chair, Founding Director of the Institute for Quantitative Biomedicine, and Director of the RCSB Protein Data Bank at Rutgers. Previously Distinguished Lilly Research Scholar in Lilly Research Laboratories, which he joined upon acquisition of SGX Pharmaceuticals where he was CSO after SGX acquisition of Prospect Genomics, which he co-founded. Prior to Prospect, Burley was Professor at The Rockefeller University and an Investigator in the Howard Hughes Medical Institute. Education: B.Sc. in Physics from University of Western Onterio, M.D. from Harvard Medical School, and D.Phil in Structural Biology from Oxford University. Internal medicine training at Brigham and Women's Hospital and postdoctoral work at Harvard and MIT.
Role: Parkinson's and enzymology expertise.
Experience: Prior Professor of Chemistry at MIT and current Professor of Neurology at Harvard Medical School where he founded the Laboratory for Drug Discovery in Neurodegeneration and directed the Morris K. Udall NIH Parkinson’s Disease Research Center of Excellence at Brigham and Women’s Hospital. Founder and CSO of Link Medicine through its sale to AstraZeneca. Currently CSO at Lysosomal Therapeutics, Inc. developing disease modifying therapies for Parkinson's disease. Education: AB (cum laude) in chemistry from Princeton University and PhD in organic chemistry from Harvard University under the direction of Nobel laureate E. J. Corey. Postdoctoral work at the Rockefeller University.